The series takes place in Cyberspace, a virtual world, and chronicles the adventures of three children, Jackie, Inez, and Matt, as they use math and problem solving skills to save Cyberspace and its leader, Motherboard, from The Hacker, the villain.
Hacker attempts to take power from the vault in Poddleville for himself by stealing the residents' power pods, much to the detriment of the community. Each power pod has a shape and a number from 1 to 12, and after Inez and Matt are imprisoned it becomes a race to solve the pattern and enter the vault.
Wicked casts a spell that erases the memories of the citizens, so that they forget how to count.
Dr. Marbles finds the encryptor chip in an ancient pyramid, but the Mummy who guards the pyramid finds Marbles. When the Cybersquad arrives, they must work their way through the chambers of the pyramid, find Dr. Marbles, and escape before a trap set by the Mummy seals them inside forever.
Dr. Marbles builds Symmetria because of his passion of symmetry, but Hacker steals the symmetrizer and destroys Symmetria by splitting everything symmetrical in half. The Cybersquad has to figure out how to get the symmetrizer back from Hacker.
The kids are assigned to steal a crystal that powers Hacker's gadgets, while distracting Hacker with a series of spa treatments.
Hacker decides he needs to change his luck from bad to good, so he hires Baskerville, a new henchman, to replace Buzz and Delete while the 10 good luck charms of Cyberspace ensure him good luck. The kids and Digit use logic to rescue the charms and stop Hacker.