Spunky daughter Kim is mortified when her bigger-than-life mom, Nikki, decides to go back to school at the same junior college she attends.
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After Kim unveils her new designs at a sorority fashion show, her creations catch the eye of Professor Oglevee's mother, Camille, who owns a chain of boutiques. Kim is thrilled when Camille places a huge order for one of her designs, but delivering the goods in time might mean putting college on hold, and incurring the wrath of Nikki.
Nikki and Kim's dream vacation in Mexico turns into a nightmare after they're kicked out of the country, and then exposed to a potentially deadly virus on the plane ride home and quarantined. Kim and Nikki go crazy under house arrest, as does Professor Oglevee when he unwittingly exposes himself to the virus by entering their house.
""T"", Kim and Stevie dream of stardom when they form a music group and then learn that the record-company exec at the career fair is an old friend of Nikki's.
Nikki's ex-fiancée walks back into her life with a promise to give up his gambling habit and a marriage proposal.
Nikki's haughty sister and her daughter come for Thanksgiving dinner and she bosses Nikki around which Nikki uncharacteristically endures.
Nikki gets involved in Professor Oglevee's mentor program, acting as a big sister for a 12-year-old girl named Shaquilla who's a handful.